Determination of acidic and basic components
Numerous pharmaceutical intermediate and end products contain acidic and basic components. These are determined by means of an appropriate acid-base titration.
Depending on the sample matrix, either aqueous or non-aqueous titrations are carried out. The latter are done with a titrant and solvent suitable for the particular application, e.g. with perchloric acid in glacial acetic acid or with tetrabutylammonium hydroxide (TBAH) in acetone
Determination of redox-sensitive components
Oxidizable and reducible components and active ingredients are determined with redox titrations. Methods frequently used include iodometry (I2/S2O42-), cerimetry (Ce(IV)), bromatometry (KBr03) and permanganometry (KMnO4). The modular structure of ProcessLab enables easy adaptation to the specific requirements of the application.
Because of its closeness to the process, the relevant analytical values are available within just a few minutes.